ESPGHAN Podcast
The ESPGHAN Podcast is the official podcast of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition. It features interviews and commentary with leading professionals, covering cutting-edge studies and practice management strategies in paediatric gastroenterology, hepatology, and nutrition. New episodes are released three times a month, on the 1st, 10th, and 20th. The podcast is hosted by the ESPGHAN Education Committee and aims to enhance knowledge and advance expertise in the field.
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Grammatikopoulos T.: Portal Hypertension – What Does Baveno Mean for Children?
Welcome back, ESPGHAN podcast listeners! Today’s discussant is Dr Tassos Grammatikopoulos, of King’s College Hospital in London, and today’s theme is portal hypertension in children, an academic interest of Dr G. Tassos, Dr Grammatikopoulos, would you please oblige me at the appropriate moment with a rimshot? I’ll cue you. Gastroenterologists and hepatologists interested in portal hypertension
Annual Meeting 2026: Highlights from Lille with Elena Cernat
Podcast listeners, we’re here today from ESPGHAN with the berry-picked best and freshest of what your society had to offer at its 58th Annual Meeting in Lille from 24 through 27 June. Mind you, “the best” reflects the opinion of our discussant, Dr Elena Cernat – she’s done the culling and the selecting. We should go into Dr Cernat’s background a bit. She comes from southeastern Romania and began
Pop T.: Wilson’s disease
Hello, trouble! Yes, we here at ESPGHAN Podcasting Central mean you, our loyal listener. But you’re only the best kind of trouble, and we’re happy to see you again. Today’s guest is Prof Tudor Pop, from Cluj-Napoca, Romania’s second city. Transylvania, the region in northern Romania in which his hometown lies, has a long and complex ethnic history. Thus, you may know Romanian Cluj-Napoca as the S
Broekaert I.: Gastrostomies and Jejunostomies
Well, would you look at that! Here’s another friend of ESPGHAN podcasting coming by to see what we have for listeners today. Welcome, and settle in for a session with a real mover and shaker, Dr Ilse Broekaert, who oversees ESPGHAN’s educational activities, and who has led efforts to introduce Europe-wide certification in paediatric gastroenterology, hepatology, and nutrition – more about this, ho
Morris T.: Preventing Metabolic Bone Disease in Children on Home Parenteral Nutrition
Good morning, evening, afternoon — whenever and wherever you may be — ESPGHAN is bringing you another podcast, this one, as we say in Hungary, egy unikum, a one-off and a first for this series. We’ve done gastroenterologists and hepatologists to death, really; it’s long been time for a new start, a new star. And we’ve found him in Dr Timothy Morris of Royal Manchester Children's Hospital, a Paedia
Alcázar López M. & Fiore G.: Microbiotia and Obesity
Mireia Alcázar López and Giulia Fiore are early-career nutrition scientists focusing on the relationship between the gut microbiome and obesity in children. Dr. Alcázar trained at Universitat Rovira i Virgili (Reus campus) in Catalonia, while Dr. Fiore trained at multiple institutions in Milan and conducted collaborative research in Reus with Dr. Alcázar. Their research investigates how caregiver
JPGN Journal Club May 2026: Emerging Insights into Eosinophilic Oesophagitis
Welcome to the third ESPGHAN Journal Club of 2026, with Dr Jake Mann! Jake has chosen for today’s session two studies in eosinophilic oesophagitis – for convenience’ sake, henceforward “EOE”. One describes an interesting rise in instances of diagnosed EOE in two regions of Spain; the other provides data suggesting that to assess EOE by both histopathologic and molecular-biologic criteria as bipart
Verduci E. & Koeglmeier J.: Vegan Diet
Dr. Elvira Verduci is a physician and clinical nutritionist at the University of Milan, where she heads the Division of Metabolic Diseases at Vittore Buzzi Children’s Hospital. She maintains a rare-disease registry for congenital defects in amino-acid metabolism and transport and serves as secretary to ESPGHAN’s Nutrition Committee. Her research interests include metabolic programming and childhoo
Walker A.: Obesity & Autism
Anna Walker is a specialist paediatric dietitian at Bristol Royal Hospital. She has a diverse international background, having been raised in Finland and educated in the United States, England, and Finland, with professional experience spanning Finland, Norway, England, and Cambodia. Her work focuses on dietetic care for children with obesity, particularly exploring the potential links between ob
Van der Doef H.: Vascular complications after Liver Transplant
Dr. Hubert P. J. van der Doef of Beatrix Children’s Hospital and the University Medical Centre Groningen, The Netherlands, trained in Utrecht and completed a fellowship in paediatric gastroenterology, hepatology, and nutrition at Groningen. He initially worked on cystic fibrosis but has since focused on vascular complications in pediatric liver transplantation, particularly how to identify and man
Vandenplas Y.: Biotics in formula
Prof Dr Yvan Vandenplas, Associate Editor of Nutrients, trained in medicine with specialty training in paediatrics at the Free University of Brussels. From the completion of his paediatric training in 1986, he moved seamlessly into an appointment in 1987 as head of the University Hospital Brussels unit for paediatric gastroenterology and nutrition. He served as Chair of Paediatrics there from 1994
JPGN Journal Club: March 2026: Biomarkers and Risk Stratification for Varices in Children with Portal Hypertension
A round of applause, dear readers: We’ve made it into, good Heavens, 2026! Breasted the tape? Or limped across the finish line? No matter. To mis-quote Scripture, that is of course Stephen Sondheim: We’re still here. Among the “we,” and our lodestar, is Dr Jake Mann. He’s selected two articles for consideration: From Jezequel M et al., in work done at Lille, J Pediatr Gastroenterol Nutr brings us
Tzivinikos C.: Magnet ingestion
Dr. Christos Tzivinikos graduated in 1999 from the Medical School of the Aristotle University of Thessaloniki, Greece. After several years serving as a medical officer aboard ships in the Greek navy, he began specialty training in paediatrics in the United Kingdom in 2005. Further training in gastroenterology followed between 2012 and 2015, culminating in a consultancy at Alder Hey Children’s Hosp
Uhlig H.: monogenic IBD: diagnosis, treatment, transition
In 1990, Prof. Holm Uhlig entered the School of Medicine at the University of Leipzig – a city in Saxony with a long and turbulent history. The University, founded in 1409, had survived centuries of upheaval, including the Battle of Leipzig in 1813, when Napoleon’s forces were defeated and King Frederick Augustus I of Saxony was taken prisoner. Studying medicine in Leipzig during the 1990s meant n
Strozyk A.: Food Ladder
Dr. Agata Stróżyk, a dietitian at the Medical University of Warsaw, shared her expertise on the “food ladder” in both theory and practice, providing insights for clinicians, patients, and families. She addresses questions such as:Could you explain what a food ladder is?What steps does a child typically go through during the food ladder process?What are the key benefits of milk and egg reintroduc
Malmberg E.: Celiac disease
Your ESPGHAN podcast team are collecting expertise from as many learnèd, skilled, and experienced paediatric gastroenterologists and hepatologists as possible! Oh, and from dietitians… they’re among the most important links in the chain between gastroenterologist and the universal goal – a healthy child and a happy family. Today’s note accompanies an encounter with Dr Elin Malmberg Hård af Segers
JPGN Journal Club January 2026: Coeliac Disease - Current Evidence on Therapy and Diagnosis
Hark! It’s midnight, children dear –Duck! Here comes another year! Well, readers, when this reaches you perhaps we shall all be in 2026, perhaps not; whichever, the New Year’s Eve couplet above may amuse you as you look backward, or forward, and… but who says that time has to be linear? Very twentieth-century idea, that – we’ve made progress since then. In any case, whenever this is, here we are.
Homan M & Giamouris V.: three tricky cases along the new HP guideline
Young ESPGHAN is on a roll! Today one of that group, a representative on the Education Committee, tries his hand at podcast interviewing: Dr Vangelis Giamouris was granted his medical degree at the University of Thessaly, trained in paediatrics in Athens at the Agia Sofia Children’s Hospital, and at present works at King’s College Hospital (London). He offers three clinical scenarios that involve
Bradley K.: ARFID
Greetings from Helsinki, where your ESPGHAN podcast team have taken the opportunity to buttonhole for interviews as many learnèd, skilled, and experienced paediatric gastroenterologists and hepatologists as possible! We haven’t forgotten the allied professions, mind you; this note accompanies for you an encounter recorded at the 2025 ESPGHAN Annual Meeting with Dr Kathryn Bradley, a clinical psyc
JPGN Journal Club December 2025: Paediatric IBD: Vedolizumab Outcomes & PSC-IBD Histopathology
Happy holidays, everyone! The end of the year… twilight falls in mid-afternoon, there’s frost on the windscreen of a morning, and between mince pies and gingerbread, the supermarket aisles are an absolute menace. But there’s hope: ESPGHAN Journal Club is here to educate, to inform, and to keep you out of trouble – whilst you’re with us you’re not flexing those credit cards, are you? Here today is
Norris H.: Nutrition in the Neonate
Welcome to the ESPGHAN podcast! Yes, it’s another of our series of interviews obtained at the sponsoring organisation’s annual meeting in Helsinki, today with Heather Norris, from Bristol. Ms. Norris trained as a dietitian – went slightly off-piste with two years of education in youth work and theology – and thereafter specialised first in paediatric nutrition and then, for the last fifteen years
Birimberg L. and Massip E.: Gastrointestinal benefits from highly effective modulator therapy in CF
Once again it’s been an unfair contest here in the ESPGHAN podcast-recording studio, little me on one side, on the other Dr. Etna Masip Simó of Valencia and Dr. Liron Birimberg-Schwartz of Jerusalem – you listeners have ringside seats for the battle, which of course Dr. Birimberg-Schwartz and Dr. Masip won without so much as trying. They are experts in the nutritional dysregulation that results f
JPGN Journal Club November 2025 - Pediatric Liver Transplantation and Sarcopenia
It’s ESPGHAN Journal Club, and—good heavens—it’s already November! Where did 2025 go? Lovely crisp sunny days, duvet-plus-blanket nights with very clingy cats, and foggy mornings with a fire in the woodstove to warm the kitchen and boil the kettle. After a nice cup of tea, let’s go shuffle-kick through the leaf piles with Dr. Jake Mann. Jake’s choices for today: From J Pediatr Gastroenterol Nutr,
Guz A.: long-term management in pediatric chronic intestinal failure
From Petah-Tikva, Israel – no map in your head? A tad east of Tel Aviv – at Schneider Children’s Medical Center, Dr. Anat Guz-Mark came to Helsinki for the ESPGHAN annual meeting, where this interview was recorded. Her particular interest and expertise lie in intestinal failure and its therapies, with surgical short-bowel syndrome, paediatric intestinal pseudo-obstruction, and a variety of congen
Grammatikopoulos T. & Ackermann O.: Portal Hypertension
Joint work, or collective work, holds out substantial promise for advancing our understanding of how pathophysiology evolves over time and how best to alter the course of disease. ESPGHAN fosters such collaboration – the podcast that this note accompanies is a good example. A recently established registry of children with portal hypertension and its complications illustrates this effort. In this
JPGN Journal Club October 2025: Advances in Pediatric Endoscopy and Ulcerative Colitis Prognostics
It’s ESPGHAN Journal Club, in your thoughts and in your ears! Thanks for tuning in to learn what Dr. Jake Mann thinks are the raisins in the loaf for this month. Jake’s choices for today:Hoskins BJ et al. (Indianapolis, Indiana, USA), J Pediatr Gastroenterol Nutr – Pediatric endoscopic mucosal resection: A 10‐year single‐center experience.Kulecka M et al. (Cork and Galway, Ireland; Málaga, Spain
Hadzic N.: Alpha 1 antitrypsin deficiency
Prof. Dr. Nedim Hadžić – Dino attended the ESPGHAN annual meeting in Helsinki. Of course, your enterprising podcast team, lurking there to glean the thoughts and insights of the best and the brightest, snapped him up for an interview! His training and early professional work were in Sarajevo, Bosnia-Herzegovina, but when he obtained a research fellowship in London, his supervisors soon recognised
Griffiths A.: Initial Workup for PIBD Diagnosis and Classification
Inflammatory bowel disease: Important to assess, to treat, and to follow correctly, as Dr Anne-Marie Griffiths of Toronto confirmed in an interview recorded in Helsinki at the ESPGHAN annual meeting. She poses for us three questions:What are some of the consequences for the patient when caregivers mislabel the type of inflammatory bowel disease?What purpose is served by thorough diagnostic evaluat
JPGN Journal Club September 2025: Innovations in Genetic Diagnosis and Therapy for Pediatric Liver Disease
Welcome back to ESPGHAN Journal Club! Give us your full attention, please – even if that means pulling into a lay-by or, even more demanding, setting down your drink. The thoughts and insights of Dr. Jake Mann are deffo worth the trouble. Jake’s choices for today:From J Pediatr Gastroenterol Nutr, by Tai CS et al., with authors from Taiwan, Thailand, and Korea: “A prediction model for genetic ch
Gottrand F.: Long-Term Follow-Up of Esophageal Atresia
Welcome to the world of oesophageal atresia and its treatment, where Prof Gottrand is eminent. (A quick hat-tip: His devotion to patient care was distinguished by the Premier prix mondial de l’atrésie de l’oesophage, awarded in June, 2019, at the World Congress on Oesophageal Atresia.) Surgical repair of oesophageal malformations yields palliation rather than cure, with a bewildering mix of dysmot
Staiano A.: ESPGHAN 100st Podcast Episode
La professoressa Annamaria Staiano è una figlia di Napoli, is a daughter of Naples, and to the city of her birth, medical education, and present professorial chair in paediatrics at the Università degli Studi di Napoli Federico II she has ever been loyal – aside from several years in St. Louis, Missouri, where she undertook subspecialty training in paediatric gastroenterology. She today is the g
JPGN Journal Club August 2025: Portal Hypertension Management and Genetic Insights in CHAPLE Disease
Summer! So hot... and everywhere is parched. The hosepipes are trickling in the twilight, both at dawn and at dusk – but is it true that watering one’s garden in the heat of the day injures the plants? Wherever you are, dear reader and listener, let’s hope it’s somewhere shady, and that on the table next to where you’ve chosen to lounge and listen is a tall glass of something with ice cubes and g
Scarallo L.: Putting intestinal ultrasound into practice
Today’s guest is Dr Luca Scarallo, one of the rising stars in the constellation of experts in inflammatory bowel disease. Dr Scarallo – I’m tempted to call him simply “Luca,” as he was born in 1993, which makes him impossibly young – comes from Benevento, lying east and south of Naples. That city, his birthplace, has a history as impossibly long as Luca is impossibly young. It flourished under th
Wine E.: New IBD Drugs in the Pipeline and How to Place Them
Dr Eytan Wine was graduated from the School of Medicine at Tel Aviv University in 1998, with training in paediatrics at Wolfson Medical Center in Holon, Israel, followed by specialty training in gastroenterology, hepatology, and nutrition at the Hospital for Sick Children in Toronto, where he also earned a PhD degree for studies in bacterially induced intestinal inflammation. His first position a
JPGN Journal Clulb July 2025: Neonatal Gut Interventions and Stem Cell Therapy for Monogenic IBD
You’ll never guess who’s across the table from me today – well, across the miles, since we’re encountering one another via ZOOM, but either way, you’ll never guess. It’s JPGN Journal Club again with... wait for it... have you marked your score sheet, folded it in quarters, and dropped it into the sealed box? No? Too late now – because it’s Dr Jake Mann! How many of you guessed right?Jake’s Picks
Assa A. & Giamouris V.: three tricky cases along the new UC guideline
Today’s podcast is a change of pace.It showcases not only Prof Dr Amit Assa, offering his expertise in approaches to treatment of paediatric ulcerative colitis, but also Dr Vangelis Giamouris, a member of Young ESPGHAN who sits on the Education Committee. Dr Giamouris has put his head over the parapet: not your usual interviewer, but instead Vangelis will shoot questions at Prof Assa; Prof Assa w
Olen O.: Cancer Risk in PIBD
A short hop from Stockholm to Helsinki, site of the 2025 ESPGHAN annual meeting, where this interview with Prof Ola Olén was recorded – in Finland, or East Sweden, as it was known until 1809, when the Treaty of Fredrikshamn / Hamina ceded both Finland and parts of both North and West Bothnia to Russia… Only in 1917 was the Grand Duchy of Finland pried away from the fragmenting Russian empire, and,
JPGN Journal Club June 2025: Pediatric Bowel Wall Sonography and Long-Term Outcomes in MASLD
Greetings from Helsinki, capital of yet another nation in which you have to watch your sushi! Boreal circumpolar dining for pescatarians… ring up another aetiology of Vitamin B12 deficiency, and check your erythrocytes’ mean corpuscular volume when you get home. At JPGN Journal Club, with Dr. Jake Mann, reaching you today from ESPGHAN’s annual meeting, we uniformly are alert against diphyllobothr
Canani B.: Ultraprocessed Food and Chronic GI Disease
Greetings from Helsinki, where your ESPGHAN podcast team has taken the opportunity to buttonhole as many learned, skilled, and experienced paediatric gastroenterologists and hepatologists as possible for interviews! This note accompanies a conversation recorded there with Dr. Roberto Canani, an expert in paediatric food allergy. In this podcast, however, he steps away from what might be considere
Annual Meeting 2025 - Highlights from Helsinki with Elena Cernat
Hot off the press – fresh from Helsinki – your ESPGHAN podcast team has interviewed Dr. Elena Cernat, a paediatric gastroenterologist originally from Romania, via Spain, and now working in Leeds. Dr. Cernat has handpicked six interesting abstracts from this year’s ESPGHAN annual meeting to discuss with us (she found many more, of course, but podcast time constraints – you’ll understand). She expl
Meyer R.: gastrointestinal manifestations of food allergy
Dr Rosan Meyer, reared and educated in South Africa and for some years active in London as a paediatric dietitian, is the guest of ESPGHAN today. Her particular interest lies in the Protean gastrointestinal manifestations of food allergy and how to intervene to reduce or to eliminate them. Today she asks us to consider : -- Are feeding difficulties adequately recognised and treated in chil
JPGN Journal Club May 2025: Noncontrast Ultrasound in Pediatric IBD and Proteotoxicity in Alpha-1-Antitrypsin Deficiency
Hello! The JPGN Journal Club, led by Dr. Jake Mann, is back — in your speakers, your earbuds, or maybe even over the airport tannoy… well, probably not the last one. Anyway, it's good to be back in touch. Please visit https://www.espghan.org/knowledge-center to explore current offerings, and don't forget ESPGHAN’s annual meeting, taking place May 14–17 in Helsinki.This session’s discussion papers
Hartleif S.: the biology of the transplanted liver
Dr. Steffen Hartleif was reared and educated in Bremen, one of the city-states in the Hanseatic League, famous for maritime trade; the son of a town and a culture that turned their backs on the land and opened their arms and hearts to the sea. Rejecting this proud heritage, he fled to southwestern Germany for medical education—almost as far from saltwater as a German can go—and has stayed there, w
Dragutinović N.: paediatric hepatogastroenterologist in Serbia
We are talking to Dr. Nataša Dragutinović, until recently of Belgrade’s University Children’s Hospital, about the difficulties — but, yes, also the joys — of training and working as a paediatric hepatogastroenterologist in Serbia, a nation shunned by the European Union since the Yugoslav Wars of the early 1990s. Resources are scant; health-care systems are underdeveloped; opportunities to travel a
JPGN Journal Club April 2025: Probiotic Therapy in Pediatric Gastroenteritis and Early-Life Sugar Exposure
Spring! The snowdrops are in their glory, the crocuses are a gaudy carpet, at least as this note is being compiled. Little darling, it’s been a long, cold, lonely winter, but here comes – no, not the Sun, instead, JPGN Journal Club, led by Dr Jake Mann. Please visit https://www.espghan.org/knowledge-center to examine the offerings, and don’t forget the Helsinki annual meeting, May 14-17, of ESP
Gutierrez C.: eosinophilic oesophagitis (EOE)
Today in the ESPGHAN podcast series we hear from Dr Carolina Gutiérrez Junquera of the Universidad Autónoma de Madrid on eosinophilic oesophagitis (EOE). Dr Gutiérrez Junquera passed in her training through the Complutense University of Madrid and its affiliated hospitals. After a fellowship in the San Francisco bay area, she went home to Spain to develop her interest in various aspects of EOE
Sigall-Boneh R.: Active Crohn’s Disease
We hear today in our ESPGHAN podcast from Dr Rotem Sigall-Boneh of Israel’s Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children’s Medical Centre, Petach-Tikva, and the Faculty of Medicine, Tel Aviv University, Tel Aviv – sorry, the “Dr” is a few months away ; she’s earning a PhD (University of Amsterdam), and it’s in the bag, I expect – who has spent the last decade app
JPGN Journal Club March 2025: Adolescent ALT Trends and Microbiome-Lipid Links to Malnutrition Cognition
Are we all recovered from January, of all months the most Monday-ish? Experience might teach us how to cope with, dear Lord, the first of three more months of winter. But no. Instead, the older one becomes, the more burdensome January is. Well, take heart: In the wonderland of JPGN Journal Club, led by Dr. Jake Mann, as the accompanying podcast is recorded, we’re deep into February. Listeners, ke
Ledder O.: Dilatation of the gastrointestinal tract in children- tips and tricks
This gem on the ESPGHAN string of pearls interviews Dr Oren Ledder, who is at once an Ozzie and an Izzie – an Australian who migrated to Israel, where he now directs the paediatric endoscopy service at Shaare Zedek Medical Center in Jerusalem. He today speaks on small-bowel stricture in inflammatory bowel disease, a focussed chat dealing with three questions in particular : 1. Which patients
Kelly D.: Long term liver transplant outcomes
Prof Dr Deirdre Kelly is today’s ESPGHAN podcast series guest, speaking on the long-term care of paediatric allograft-liver patients and the findings gleaned from protocol-biopsy studies. These have uncovered inflammation and fibrosis that are not clinically apparent ; although shifts in immunosuppressive regimen can ablate inflammation, fibrosis persists. (These findings come from patients who
JPGN Journal Club February 2025: Serum Bile Acids in Biliary Atresia and ITGAV Variants in Immune Dysregulation
At the watershed between 2024 and 2025, some readers will have remembered this couplet: “Hark! It’s midnight, children dear. / Duck – here comes another year!” In paraphrase, then, duck – here comes another instalment of JPGN Journal Club, led by Dr. Jake Mann! Before we move along to the articles to which Jake wants us to pay attention, have a glance at what ESPGHAN is doing for you at https://
Bontems P.: Capsule endoscopy in children
An old friend today – scratch that, a familiar friend – familiar to those who have followed these podcasts since their inception : Welcome to the studio from Brussels, Dr Patrick Bontems, head of “interventional paediatrics” at Hôpital Universitaire des Enfants Reine Fabiola ! This is his second appearance as an ESPGHAN guest, and we’re delighted to have him back to speak on aspects of percutane
Hyer W.: the management of polyposis syndromes in paediatric patients
Three for two today ; one interviewer and two guests, Dr Warren Hyer and Ms Fiona Cargill-Marin in this ESPGHAN podcast, with its theme the management of polyposis syndromes in paediatric patients : Not so much the from-what-age and the what-to-look-for as the origin of the guidelines first put forward by ESPGHAN going on five years ago and spearheaded by Dr Hyer, who is among the leaders of a we
JPGN Journal Club January 2025: Paediatric Crohn’s Disease Management and Failure-to-Rescue Insights in Liver Transplantation
Happy holidays, everyone! Here’s JPGN Journal Club, led by Dr Jake Mann. Don’t forget ESPGHAN’s other educational offerings: https://www.espghan.org/knowledge-center – on 2025.I.15 the GI Winter School, on I.30 the Monothematic Conference on Steatotic Liver Disease in Children, and on III.05 the GI Immunology Master Class: From pathogenesis to clinical management of EGID, coeliac disease, and IBD
Moltu S.: Nutrition for the critically ill neonate
The ESPGHAN podcast series today hopes to make you familiar with some of the work of Dr Sissel Moltu, a polyglot and polymath – she’s of Norwegian and USAnian heritage, was reared in Norway, took her medical degree in Freiburg, worked in England – who combined neonatology with gastroenterology when in Oslo University Hospital frustration at parenteral-alimentation – associated liver disease in sho
Kamath B.: Alagille - A multifaceted condition
Prof Dr Binita Kamath of first the United Kingdom (London’s King’s College Hospital), then the United States (Children’s Hospital of Philadelphia), then Toronto’s Hospital for Sick Children – and now, wait for it, the Children’s Hospital of Philadelphia again ! – speaks with us today in the ESPGHAN podcast series. She has seen diagnosis of Alagille syndrome (AGS) move from clinicomorphologic asse
JPGN Journal Club December 2024: Human Milk in Biliary Atresia and Type III Interferon–Induced Pyroptosis in Gut Epithelium
December’s almost here, can you believe it ? Here’s JPGN Journal Club, led by Dr Jake Mann ! Don’t forget ESPGHAN’s other educational offerings : https://www.espghan.org/knowledge-center – on XII.27 the MOOC Enteral Nutrition in Preterm Infants conference, on 2025.I.01 the Young ESPGHAN Mentorship Programme, on I.15 the GI Winter School, and on I.30 the Monothematic Conference on Steatotic Live
Campoy C.: Childhood Obesity Prevention: Impact of nutrition during pregnancy
The ESPGHAN podcast series today addresses three points that have defined the recent career of Dr Cristina Campoy Folgoso, professor and chair of paediatrics at the Medical University of Granada, Spain. These ar : How maternal nutritional status can determine the offspring's growth and body composition during childhood ; which interventions during pregnancy may effectively prevent childhood obesi
Dinning A.: Short Bowel Syndrome
Today’s ESPGHAN podcast series guest, Mrs Alison Dinning, is an academic dietitian at the Children’s Hospital of Bristol in the west of England. Her interests centre on the care of children with short-bowel syndrome (SBS), with particular pleasure taken in successful shifts from parenteral to enteral alimentation – hard work, but if the family can be brought on board, then with use of breast milk
JPGN Journal Club November 2024: Rapid Infliximab Monitoring and Lipid Profiling for Pediatric Obesity Risk
November: Knocking on the door, or already inside and making itself at home ? Whatever. It’s JPGN Journal Club, led by Dr Jake Mann! Don’t forget ESPGHAN’s other educational offerings: https://www.espghan.org/knowledge-center – in particular on XI.11 the Winter School on Basic Science and Translational Research; on XI.15 a Masterclass on Transition from Paediatric to Adult Healthcare in Patient
DeLaffolie J.: Artificial Intelligence
Today’s ESPGHAN podcast interviews Dr Jan de Laffolie, at present in Giessen (Germany), who has a strong interest in both inflammatory bowel disease and in “artificial intelligence”, or AI – that is, the sifting of data for correlations, not only those that are apparent to humans unassisted, call it to the naked eye / the naked mind, but also those that elude us mortals when we are on our own. Wo
Dunitz-Scheer M.: Return to meal. Successful weaning from tube-feeding
Turmoil after Hitler’s war brought together the parents of today’s guest, Dr Marguerite Dunitz-Scheer ; she was born in the United States, reared in Switzerland, and with a marriage became Austrian. She might have become a musician by profession – that was in her family’s blood, and she attended a conservatory as a teenager – but instead, true to the principle of everything, everywhere, and all a
JPGN Journal Club October 2024: Home Parenteral Nutrition in Neurologically Impaired Children and TNFRSF12A as a Therapeutic Target in Biliary Atresia
October JPGN Journal Club, led by Dr Jake Mann ! As always, keep in mind ESPGHAN’s other educational offerings : https://www.espghan.org/knowledge-center – in particular on X.25 a Monothematic Conference on Paediatric Gastric Disease ; on XI.11 the Winter School on Basic Science and Translational Research ; and on XI.15 a Masterclass on Transition from Paediatric to Adult Healthcare in Patients
Waisbourd-Zinman O.: Unravelling the pathogenesis of biliary atresia
Interviewed today in the ESPGHAN podcast series is Dr Orit Waisbourd-Zinman, of Israel, who as a fellow in hepatology at the Children’s Hospital of Philadelphia was offered the chance to take part in studies of how “biliatresone”, a compound isolated from Australian plants (Dysphania sp.), might disrupt formation of extrahepatic biliary structures, as was postulated when sheep during drought ate u
Escher H.: Tips and tricks for a successful transition, is there any evidence?
Dr Johanna (“Henkje”) Escher speaks with me for ESPGHAN’s podcast series today. She works in learning how best to pass along the care of paediatric patients when, rather arbitrarily, they are declared to be adults. All very well, no adolescent wants to be a child forever, but . . . well, paediatric disorders, that is, those that manifest themselves in early life, cover a far wider spectrum than
JPGN Journal Club September 2024: Post-Transplant Pediatric IBD and Long-Term Outcomes in Autoimmune Sclerosing Cholangitis
JPGN Journal Club, led by Dr Jake Mann, is here again for August. As always, keep in mind ESPGHAN’s other educational offerings : https://www.espghan.org/knowledge-center – in particular on IX.12, AHP Summer School ; IX.21, the Young Investigator Forum ; IX.25, the 5th Liver Transplant School ; and X.25, a Monothematic Conference on Paediatric Gastric Disease. For today’s discussion Jake has chos
Lanigan J.: Complementary feeding - new WHO guideline
Interviewed today in the ESPGHAN podcast series is Dr Julie Lanigan of University College London, working at several hospitals in London and lecturing in Plymouth, a dietitian whose interest is in complementary feeding (once called “weaning”, or the introduction of foods other than milk to an infant’s diet). Not just foods, but feeding, taking part in the activities that define the family – gaini
Norsa L.: Teduglutide in short bowel syndrome
Bergamascheria ancora! Yes, the Bergamo team have made available for a podcast yet another member, Dr Lorenzo Norsa, a professor of paediatrics there. Dr Norsa has been a fellow in paediatric gastroenterology in Israel and in France. In Paris he became well-versed in treatment of short bowel syndrome, working with the prominent Necker team . . . perhaps their publications form a suite Bergamasqu
JPGN Journal Club August 2024: Pediatric Autoimmune Gastritis and Predicting Liver Fibrosis in MASLD
It’s JPGN Journal Club, led by Dr Jake Mann, in your electronic- device speakers, with the July podcast offering. Don’t forget to check out what ESPGHAN has available from July onward, here at https://www.espghan.org/knowledge-center -- in particular on IX.12, AHP Summer School, IX.21, the Young Investigator Forum, and on IX.25, the 5th Liver Transplant School. Jake Mann has chosen for today’s di
Marra P.: The nick of time - an IR approach to managing upper GI bleeding
The ESPGHAN podcast guest today is Dr Paolo Marra – the interviewer, as our producer, Selma Ertl already has told you, is same old same old me – to round out the team, a hat-tip to Manuel Schuster, engineer. Let’s get starty with the party! So, Dr Marra – an interventional radiologist, and like everyone across from whom I sit in these sessions, amazingly young to have accomplished so much. He is
Papadopoulou A.: Pitfalls in the diagnosis and management of children with non-EoE EGIDs
Interviewed today in the ESPGHAN podcast series is Hon. Prof. Dr. med. Alexandra Papadopoulou from Greece, Chair of the ESPGHAN Working Group and Special Interest Group on Eosinophilic Gastrointestinal Disorders for the last six years, Head of the Division of Gastroenterology, Hepatology and Nutrition of the First Department of Pediatrics of the National and Kapodistrian University of Athens and H
JPGN Journal Club July 2024: Intestinal Rehabilitation in Congenital Diarrhea and Biomarker-Based Prognosis After Pediatric Liver Transplantation
JPGN Journal Club reporting for duty, sah! And mem! Here’s the spoken word about the written word . . . in a glorious June, with Heaven and Earth well and true in tune, as the poem goes. Don’t forget to check out what ESPGHAN has on offer from July onward, available at https://www.espghan.org/knowledge-center ! Dr Jake Mann has chosen for today’s discussion two heavy-hitting publications. The f
Assa A.: New biologics and other new therapies for the treatment of IBD
ESPGHAN presents today an encounter with Prof Amit Assa, who like so many of those who have agreed to take part in these podcasts has filled all the posts of the medical-school and medical-administrative cursus honorum, steadily leaping upward from institution to institution. As of now he is at the Institute of Paediatric Gastroenterology, Shaare Zedek Medical Centre, in Jerusalem, Israel (affili
Koot B.: MASLD
Today’s ESPGHAN podcast offers the opportunity to become acquainted with the effects of a revision in nomenclature. Decades ago, stout – in both senses – Mormon matrons were vastly offended to learn that the form of steatohepatitis from which they suffered was histopathologically superimposeable upon that owing to ingestion of ethanol to excess ; the Word of Wisdom, a revelation vouchsafed in 183
JPGN Journal Club June 2024: Anti-TNF Resistance in IBD and SIPR2 Pathways in Cholestasis with Prof Binita Kamath and Dr Jake Mann
JPGN Journal Club reports from the Milan venue of ESPGHAN’s 2024 annual meeting, seizing the opportunity to learn from those rarely in Europe – as today with Prof Binita Kamath, in transit between Toronto and Philadelphia professionally, who along with Dr Jake Mann will tag-team her way down the field shooting for goal with two articles of interest (Winter et al.’s Biomarkers predicting the effect
Annual Meeting 2024 - Highlights from Milan
O-makase is the word of the day, the phrase that in Japan tells your chef that your meal is both literally and metaphorically in her hands – “Choose for me,” it means. Most fine dining has an equivalent; the French say menu de dégustation, here in Milan / Mailand / Milano it’s called menù degustazione. That is: Non prevede scelte da parte del cliente! You, the diner, have no say. Either eat what’s
Vandenplas Y.: feeding disorders of infancy and in cows’-milk allergy
Dr Alex Knisely today speaks with Prof Yvan Vandenplas of Brussels, where he was chief of paediatrics for many years. He’s a hollow-viscus gastroenterologist rather than a “liver man”, and he has made many contributions in his chosen field, particularly in feeding disorders of infancy and in cows’-milk allergy, a topic on which he has selected three articles for us, all published in 2023 : From JP
JPGN Journal Club May 2024: Genetic Insights in Cystic Fibrosis Liver Disease and Linaclotide for Pediatric Functional Constipation
Here again is JPGN Journal Club. It’s Spring, people! Asparagus! Strawberries! White wine! All of these can be enjoyed as an ESPGHAN podcast listener, so let’s get at it : Raise your sauce béarnaise-laden forks, your Sancerre glasses, and your play-volume settings. Dr Jake Mann has chosen for today from Hepatology, by Stonebraker et al., Genetic variation in severe cystic fibrosis liver disease
Vogel G. F.: ileal bile-acid transport inhibitor, odevixibat
Dr. Alex Knisely today is talking to Dr. Georg-Friedrich Vogel – call him “Georg” – of the Medizinische Universität Innsbruck, in Austria, where he serves on the paediatric-hepatology wards and conducts research in the department of cell biology. In Vienna this May, at the ESPGHAN annual meeting, he presented observations on the utility of an ileal bile-acid transport inhibitor, odevixibat (those
JPGN Journal Club April 2024: Oral Vancomycin in PSC-IBD and Referral Patterns for Biliary Atresia in Europe
JPGN Journal Club is again here for you! No, no point in all that applause, although we’re grateful: Remember, we can’t hear it. As always, we’re glad to be back and we hope that you’re glad to have us back. Dr Jake Mann has chosen for today from Aliment Pharmacol Ther, by Ricciuto et al., Oral vancomycin is associated with improved inflammatory bowel disease clinical outcomes in primary sclerosi
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